Sporos BioDiscovery to Present Preclinical Findings on SPR1, a Next-Generation TEAD Inhibitor, at the American Association for Cancer Research (AACR) Annual Meeting 2024
Mar 6, 2024 | Press Releases
HOUSTON, Texas., March 6, 2024 — Sporos BioDiscovery, Inc. (a portfolio company of Sporos Bioventures, LLC.), a precision oncology company developing a diversified pipeline of small molecule therapeutic programs targeting cancer vulnerabilities in the tumor and tumor microenvironment, today announced that it will present two posters highlighting preclinical data from the company’s novel, TEAD1 / TEAD4 isoform selective inhibitor, SPR1, at the American Association for Cancer Research (AACR) Annual Meeting 2024 taking place April 5-10, 2024, in San Diego, CA.
“We look forward to presenting two posters at this year’s AACR meeting that highlight the significant preclinical work we have done to characterize SPR1 as a potential best-in-class TEAD inhibitor. In addition, our team’s expert biological analysis has uncovered a new therapeutic vulnerability that could broaden the potential use of SPR1, a TEAD1/4 inhibitor, to a new subset of cancers with certain homozygous deletions,” said Stephen Rubino, Ph.D., President of Sporos BioDiscovery.
Presentation Details
- Title: TEAD1/4 inhibitors exhibit deeper biological impact and broader activity compare to TEAD1 only inhibitors in both monotherapy and combination without additional kidney toxicity
- Session Category: Experimental and Molecular Therapeutics
- Session Title: New Targets
- Session Date and Time: Tuesday, Apr 9, 2024, 1:30 p.m. – 5:00 p.m. PT
- Abstract Number: 5913
- Poster Number: 27
- Title: VGLL4 is the target of the 3p25 homozygous deletion and presents a novel therapeutic vulnerability for TEAD1/4 but not TEAD1 inhibitors
- Session Category: Experimental and Molecular Therapeutics
- Session Title: YAP/TAZ/TEAD Modulators
- Session Date and Time: Wednesday Apr 10, 2024, 9:00 a.m. – 12:30 p.m. PT
- Abstract Number: 7266
- Poster Number: 3
About Sporos BioDiscovery
Sporos BioDiscovery, Inc. is a biotechnology research & development company with a diversified pipeline of several small molecule precision oncology therapeutic programs in development, including its lead candidate SPR1, a novel TEAD inhibitor program. Sporos BioDiscovery, Inc. is a portfolio company of Sporos Bioventures, LLC, a private biotechnology company focused on transforming the drug development process across oncology.
Media and Investor Contact
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